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January 2007 »

Analysis confirms ED drugs OK for diabetic men

24 January, 2007

Viagra and similar drugs used to treat erectile dysfunction, often referred to as ED, work for men with diabetes and appear to be safe, according to a research review being published Wednesday.

Diabetes is one of the most common causes of ED, and experts estimate that diabetic men are about three times more likely than other men to deal with erection problems at some point.

ED is also typically more severe and difficult to treat in men with diabetes, Dr. Moshe Vardi, of Lady Davis Carmel Medical Center in Israel, told Reuters Health.

To assess the safety and effectiveness of ED drugs for diabetic men, Vardi's team reviewed eight clinical trials conducted since 1998. Each compared one of three ED drugs on the market -- Viagra, Levitra or Cialis -- with a placebo, or inactive pill.

All three drugs belong to a class of medications called phosphodiesterase-5 (PDE-5) inhibitors, which enhance blood flow to the penis and can allow men with ED to maintain an erection.

Together the drugs have "altered the management" of ED in general, Vardi said, but until now there had been no systematic review of how well the drugs work for diabetic men.

Across the eight studies Vardi's team analyzed, the 976 men who were given a PDE-5 inhibitor were nearly four times more likely than the 741 given a placebo to say the treatment had improved their sexual function.

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